Universidad del País Vasco (UPV/EHU)

Actualizado el 08-02-2010

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Publicaciones

Hedgehog signaling is critical for normal liver regeneration after partial hepatectomy in mice. Begoña Ochoa, Wing-Kin Syn, Igotz Delgado, Gamze F. Karaca, Youngmi Jung, Jiangbo Wang, Ana M. Zubiaga, Olatz Fresnedo, and Anna Mae Diehl. Hepatology 2009 (in press)

A subset of dysregulated metabolic and survival genes is associated with severity of hepatic steatosis in obese Zucker rats.
Buque X, Martinez MJ, Cano A, Miquilena ME, Garcia-Monzon C, Aspichueta P, Ochoa B.
J Lipid Res. 2009 Sep 24. [Epub ahead of print]

Interleukin-6 is associated with liver lipid homeostasis but not with cell death in experimental hepatic steatosis.
Sánchez-Garrido MA, Chico Y, González R, Ranchal I, González-Rubio S, Hidalgo AB, Díaz-López C, Costán G, Padillo FJ, De la Mata M, Ochoa B, Muntané J.
Innate Immun. 2009 Aug 26. [Epub ahead of print]

Hepatic VLDL assembly is disturbed in a rat model of nonalcoholic fatty liver disease: is there a role for dietary coenzyme Q?
Cano A, Ciaffoni F, Safwat GM, Aspichueta P, Ochoa B, Bravo E, Botham KM.
J Appl Physiol. 2009 Sep;107(3):707-17. Epub 2009 Jul 16.

[Molecular basis of obesity-related hepatic steatosis]
Buqué X, Aspichueta P, Ochoa B.
Rev Esp Enferm Dig. 2008 Sep;100(9):565-78. Spanish

Profiling and imaging of lipids on brain and liver tissue by matrix-assisted laser desorption/ ionization mass spectrometry using 2-mercaptobenzothiazole as a matrix.
Astigarraga E, Barreda-Gómez G, Lombardero L, Fresnedo O, Castaño F, Giralt MT, Ochoa B, Rodríguez-Puertas R, Fernández JA.
Anal Chem. 2008 Dec 1;80(23):9105-14.

Kupffer cell products and interleukin 1beta directly promote VLDL secretion and apoB mRNA up-regulation in rodent hepatocytes.
Bartolomé N, Arteta B, Martínez MJ, Chico Y, Ochoa B.
Innate Immun. 2008 Aug;14(4):255-66.

Upregulation of apolipoprotein B secretion, but not lipid, by tumor necrosis factor-alpha in rat hepatocyte cultures in the absence of extracellular fatty acids.
Bartolomé N, Rodríguez L, Martínez MJ, Ochoa B, Chico Y.
Ann N Y Acad Sci. 2007 Jan;1096:55-69.

NF-Y and Sp1 are involved in transcriptional regulation of rat SND p102 gene.
Rodríguez L, Ochoa B, Martínez MJ.
Biochem Biophys Res Commun. 2007 Apr 27;356(1):226-32. Epub 2007 Feb 28.

La infección de hepatocitos de rata en cultivo con adenovirus recombinantes causa un drástico descenso en la secreción de lipoproteínas de muy baja densidad
L Palacios. O Fresnedo. I García-Arcos. JV Castell. B Ochoa.
Clin Invest Arterioscl. 2006;18:9-17.

Isolation and characterization of the rat SND p102 gene promoter: putative role for nuclear factor-Y in regulation of transcription.
Rodríguez L, Bartolomé N, Ochoa B, Martínez MJ.
Ann N Y Acad Sci. 2006 Dec;1091:282-95.

Overexpression of SND p102, a rat homologue of p100 coactivator, promotes the secretion of lipoprotein phospholipids in primary hepatocytes.
Palacios L, Ochoa B, Gómez-Lechón MJ, Castell JV, Fresnedo O.
Biochim Biophys Acta. 2006 Jul;1761(7):698-708. Epub 2006 May 19.

Impaired response of VLDL lipid and apoB secretion to endotoxin in the fasted rat liver.
Aspichueta P, Pérez-Agote B, Pérez S, Ochoa B, Fresnedo O.
J Endotoxin Res. 2006;12(3):181-92.

The 2-series prostaglandins suppress VLDL secretion in an inflammatory condition-dependent manner in primary rat hepatocytes.
Pérez S, Aspichueta P, Ochoa B, Chico Y.
Biochim Biophys Acta. 2006 Feb;1761(2):160-71. Epub 2006 Mar 3.

La lipidómica, una nueva herramienta al servicio de la salud.
Begoña Ochoa
Gaceta Médica Bilbao ISSN 0394-4858. 2006 Vol. 103 Num. 3 Págs: 101-102
[Resumen] [PDF]

Endotoxin promotes preferential periportal upregulation of VLDL secretion in the rat liver.
Aspichueta P, Pérez S, Ochoa B, Fresnedo O.
J Lipid Res. 2005 May;46(5):1017-26. Epub 2005 Feb 16.

The fatty acid composition of chylomicron remnants influences their propensity to oxidate.
Napolitano M, Bravo E, Avella M, Chico Y, Ochoa B, Botham KM, Rivabene R.
Nutr Metab Cardiovasc Dis. 2004 Oct;14(5):241-7.

Differential modulation of prostaglandin receptor mRNA abundance by prostaglandins in primary cultured rat hepatocytes.
Pérez S, Maldonado EN, Aspichueta P, Ochoa B, Chico Y.
Mol Cell Biochem. 2004 Nov;266(1-2):183-9.

 

Sequences

AAU05374
SND p102 [Rattus norvegicus]
gi|51512262|gb|AAU05374.1|[51512262]
Palacios,L., Fresnedo,O. and Ochoa,B. (2004)

AY697864
Rattus norvegicus SND p102 mRNA, complete cds
gi|51512261|gb|AY697864.1|[51512261]
Palacios,L., Fresnedo,O. and Ochoa,B. (2004)

AY957585
Rattus norvegicus SND p102 gene, promoter and 5' UTR sequence
gi|62183810|gb|AY957585.1|[62183810]
Rodriguez,L., Martinez,M.J. and Ochoa,B. (2005)

EF690304
Homo sapiens staphylococcal nuclease and tudor domain containing 1 (SND1) gene, partial sequence.
gi|154163175|gb|EF690304.1|[154163175]
Rodriguez,L., Martinez,M.J. and Ochoa,B. (2007)

 

ARRAY EXPRESS

Transcription profiling of liver from mouse EF2 mutants vs wild type to investigate the role of E2F2 in liver regeneration
Igotz Delgado
E-MEXP-1413, 2008-01-18
http://www.ebi.ac.uk/microarray-as/ae/browse.html?keywords=E-MEXP-1413

Transcription profiling of hepatocyes from Zucker fa/fa obese rats vs controls
Xabier Buqué
E-MEXP-1414, 2008-01-18
http://www.ebi.ac.uk/microarray-as/ae/browse.html?keywords=STEATOSIS&species=Rattus+norvegicus&array=&exptype=&pagesize=25&sortby=releasedate&sortorder=descending